禁忌书屋

赵琦 教授

作者:时间:17-05-09 15:30浏览:字体:



 


姓名:赵琦

,博士研究生,教授,硕士生导师

禁忌书屋 组织部部长、禁忌书屋 生物工程领域教师

电子邮件:zhaoqi@cdu.edu.com

简历

禁忌书屋 “川藏特色药用植物资源开发利用四川省教育厅高校工程研究中心”负责人主持国家自然科学基金、四川省杰出青年科技人才项目、科技支撑项目等省部级以上课题10余项。以第一或通讯作者在Phytomedicine、Plant Physiology and Biochemistry Journal of Ethnopharmacology、BMC Plant Biology、《中草药》、《分子植物育种》等国内外知名学术期刊发表论文50余篇在科学出版社出版专著1部授权发明专利5项培养研究生20余名。

2009年07月—2013年12月   禁忌书屋   药学与生物工程学院   讲师

2014年01月—2014年12月   禁忌书屋   药学与生物工程学院   副教授

2014年12月—2019年11月   禁忌书屋   科技处               副处长

2019年11月—2022年11月   禁忌书屋   科技处               处长

2022年12月—2023年05月   禁忌书屋   研究生处             处长

2023年05月—2024年12月   禁忌书屋   人事处               处长

2024年12月--至今           禁忌书屋   组织部               部长

 

社会任职

四川省杰出青年科技人才

四川省学术技术带头人后备人选

四川省植物学会副理事长

主要研究方向:

  1. 重要活性天然产物的生物合成规律及调控研究

  2. 活性天然产物靶标鉴定和作用机制研究

主要教学成果:

  1. 国家级生物科学实验教学示范中心实验教学模式创新的探索,国家级教学成果奖二等奖(排名第六),2014

  2. 地方高校生物产业类应用型人才培养模式的构建与实践,四川省优秀教学成果二等奖(排名第五),2015

  3. 《中国西南农村能源生态建设发展分析》(专著),四川省第十九次社会科学优秀成果奖(排名第二),2022

 

主要科研项目及成果:

  1. 国家自然科学基金面上项目,32570437,“SSR-AOP2-CYP90B1基因簇介导川贝母异甾体生物碱合成的机制解析”,2026.01-2029.12,50万元,在研,主持

  2. 国家自然科学基金面上项目,32270407,“基于TRPV1通路的川贝母栽培品镇咳药效物质基础研究”,2023.01-2026.12,54万元,在研,主持

  3. 国家自然科学基金青年项目,31600261,“卷叶贝母再生鳞茎生物碱高效累积相关基因资源发掘与激素调控激励研究”,2017.01-2019.12,20万元,已结题,主持

  4. 四川省杰出青年科技人才项目,2022JDJQ0053,“不同基原川贝母镇咳药效的物质基础研究”,2022.01-2024.12,20万元,已结题,主持

  5. 四川省省科技厅应用基础项目,2018JY0296,“西贝母碱与化疗药联用对人肺癌细胞耐药性的逆转效果研究”,2018.01-2020.12,10万元,已结题,主持

  6. 四川省科技厅科技支撑项目,2013RZ0017,“川贝母组织培养中甾类生物碱累积的分子基础”,2013.10-2014.09,10万元,已结题,主持

  7. 四川省科技厅应用基础项目,2013JY0057,“四川油橄榄主产区产油地域性差异的分子基础研究”,2013.01-2015.12,10万元,已结题,主持

  8. 成都市产业升级牵引工程-农业技术研发项目,2015-NY02-00366-NC,“卷叶贝母工厂化繁育技术研究与开发”,2017.06-2019.05,20万元,已结题,主持

  9. Min Sun, Qin Jiang, Enhao Zhang, Ziwei Zhu, Yixi Yang, Chunlin Tan, Zhiqiang Wang, Rui Li*, Yang Tao*, Qi Zhao*. Evolutionary Dynamics and Functional Diversification of bZIP Transcription Factors in Cucurbitaceae: A Pan-Genome Approach. Journal of Agricultural and Food Chemistry. 2025,73, 50, 32363-32378

  10. Daihan Chen, Min Sun, Yixi Yang, Benyi Tan, Dongsheng Ren, Yang Tao, Rui Li, Qi Zhao*. Comprehensive genome-wide analysis and functional characterization of the DIR gene family in Herpetospermum pedunculosum: insights from HpDIR16 and HpDIR17. Plant Physiology and Biochemistry. 2025,226,110074

  11. Yu Xiao, Tianfeng Luo, Changsong Duan, Xinhui Wang, Yixi Yang, Rui Li, Jinpeng Deng, Qi Zhao*. Ethyl acetate extract from Herpetospermun cardigerum wall. Ameliorated concanavalin A-induced autoimmune hepatitis in mice by reprofiling gut microenvironment to modulate IDO1/KYN and PI3K/AKT/NF-κB pathways. Journal of Ethnopharmacology. 2025,345,9:119578

  12. Yu Wang, Meihao Peng, Xin Yang, Liming Tu, Jiamin Liu, Yixi Yang, Rui Li, Xue Tang, Yuqing Hu, Guowu Zhang, Qi Zhao*, Qiuxia Lu*. Total alkaloids in Fritillaria cirrhosa D. Don alleviate OVA-induced allergic asthma by inhibiting M2 macrophage polarization. Journal of Ethnopharmacology. 2025,337:118935

  13. Mingcheng Wang, Shuqiao Zhang, Rui Li, Qi Zhao*. Unraveling the specialized metabolic pathways in medicinal plant genomes: a review. Frontiers in Plant Science. 2024, 15,1459533

  14. Ziwei Zhu, Daihan Chen, Min Sun, Maotao Xiao, Peng Huang, Dongsheng Ren, Yixi Yang, Zhen Zhang, Qi Zhao*, Rui Li*. Integrative analysis of the metabolome and transcriptome provides insights into the mechanisms of lignan biosynthesis in Herpetospermum pedunculosum (Cucurbitaceae). BMC Genomics,2024, 25:421

  15. Meihao Peng, Jintao Li, Jie Zhou, Bowen Zhang, Jiaqing Liao, Di Yang, Yu Wang, Yixi Yang, Rui Li, Xue Tang, Qiuxia Lu*, Qi Zhao*. Total alkaloids of Fritillaria unibracteata var. wabuensis bulbus ameliorate chronic asthma via the TRPV1/Ca2+/NFAT pathway. Phytomedicine. 2023, 118: 154946

  16. Yixi Yang, Bowen Zhang, Ying Bao, Peng Huang, Jian Li, Rui Li*, Qi Zhao*. Chromosome-level genome assembly of Herpetospermum pedunculosum (Cucurbitaceae). Genome Biology and Evolution. 2023,15(2): evad005

  17. Ya Zhong, Bowen Zhang, Jintao Li, Xin Zeng, Junxia Pei, Yamei Zhang, Yixi Yang, Fulun Li, Yu Deng*, Qi Zhao*. Ethanol extract of Herpetospermum caudigerum Wall ameliorates psoriasis-like skin inflammation and promotes degradation of keratinocyte-derived ICAM-1 and CXCL9. Journal of Integrative Medicine. 2023, 21, 6: 584-592

  18. Mingcheng Wang, Rui Li, Qi Zhao*. Multi-Omics Techniques in Genetic Studies and Breeding of Forest Plants. Forests. 2023,14(6), 1196

  19. Qiuxia Lu, Rui Li, Jiaqing Liao, Yuqin Hu, Yundong Gao, Mingcheng Wang, Jian Li*, Qi Zhao*. Integrative analysis of the steroidal alkaloids distribution and biosynthesis of bulbs Fritillaria Cirrhosae through metabolome and transcriptome analyses. BMC genomics. 2022, 23(1): 511

  20. Yixi Yang, Yujin Zhang, Xun Chen, Zhou Su, Yu Deng, Qi Zhao*. Khasianine ameliorates psoriasis-like skin inflammation and represses TNF-α/NF-κB axis mediated transactivation of IL17A and IL-33 in keratinocytes. Journal of Ethnopharmacology. 2022, 292: 115124

  21. Jian Li, Feng Zhao, Wenyao Zhan, Zhiqi Li, Liang Zou, Qi Zhao*. Challenges for the application of bacteriophages as effective antibacterial agents in the food industry. Journal of the Science of Food and Agriculture. 2022,102(2):461-471

  22. Rui Li, Yang Zhang, Yucheng Wang, Kejia Huang, Qianye Yang, Tiantian Zhang, Kun Xie, Jian Li*, Qi Zhao*, Aqueous extract of Fritillariae cirrhosae induces cellular apoptosis through activation of STATs-mediated immunomodulation. Journal of Ethnopharmacology. 2020, 261

  23. Wenguo Wang, Rui Li, Hong Wang, Bufan Qi, Xiaomei Jiang, Qili Zhu, Denggao Cai, Xiaoyu Tang*, Qi Zhao*. Sweetcane (Erianthus arundinaceus) as a native bioenergy crop with environmental remediation potential in southern China: A review. GCB Bioenergy. 2019,11(9):1012-1025

  24. Zhiqiang Wang, Kailiang Yu, Shiqi Lv, Karl J. Niklas, Tserang Donko Mipam, Thomas W. Crowther, María N. Umaña, Qi Zhao*, Heng Huang*, and Peter B. Reich. The scaling of fine root nitrogen versus phosphorus in terrestrial plants: a global synthesis. Functional Ecology. 2019,33, 11: 2081-2094

  25. Jian Li, Wenwen Li, Kejia Huang, Yang Zhang, Gary Kupfer, Qi Zhao*. Chimeric Antigen Receptor T cell (CAR-T) immunotherapy for solid tumors: lessons learned and strategies for moving forward. Journal of Hematology & Oncology. 2018,11 (1), 22

  26. Jian Li, Qianye Yang, Yang Zhang, Kejia Huang, Rong Sun, Qi Zhao*. Compound F779-0434 causes synthetic lethality in BRCA2-deficient cancer cells by disrupting RAD52–ssDNA association. RSC Advances. 2018,8, 18859-18869

  27. Qi Zhao, Rui Li, Yang Zhang, Kejia Huang, Wenguo Wang*, Jian Li*. Transcriptome analysis reveals in vitro-cultured regeneration bulbs as a promising source for targeted Fritillaria cirrhosa steroidal alkaloid biosynthesis. 3 Biotech. 2018,8(4):191

  28. Qi Zhao, Rui Li, Yingying Gao, Xiaoqiang Guo, Wenguo Wang, Modeling impacts of climate change on the geographic distribution of medicinal plant Fritillaria cirrhosa D. Don. Plant Biosystems. 2018, 152(3): 349-355

  29. Wenguo Wang, Rui Li, Qili Zhu, Xiaoyu Tang, Qi Zhao*. Transcriptomic and physiological analysis of common duckweed Lemna minor responses to NH4+ toxicity. BMC Plant Biology. 2016,16(1):92